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编 号:F389599
分子式:C33H40O20
分子量:756.66
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生物活性:
Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research.

体外研究:
The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM.Plantanone B?inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively..Plantanone B?shows significant COX-1 and moderate COX-2 inhibitory activities with IC50?values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively.
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