产品
编 号:F043646
分子式:C16H18N4O3S
分子量:346.4
产品类型
结构图
CAS No: 113712-98-4
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产品详情
生物活性:
Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor with a prolonged plasma half-life. Tenatoprazole inhibits hog gastric H+/K+-ATPase activity with an IC50 of 6.2 μM. Tenatoprazole blocks the interaction of ubiquitin with the ESCRT-1 factor Tsg101, inhibits production of several enveloped viruses, including EBV.
体外研究:
Tenatoprazole (TU-199) (0.1、0.2、0.4 mg/kg;口服;单只;Heidenhain-pouch 犬) 剂量依赖性地抑制组胺输注刺激的胃酸分泌。