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编 号：F388585
分子式：C53H84O23
分子量：1089.22
分子式：C53H84O23
分子量：1089.22
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CAS No: 55446-15-6
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生物活性：
Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury.
体外研究：
Araloside C also up-regulates the expression levels of Hsp90 and improved cell viability in hypoxia/reoxygenation-treated H9c2 cardiomyocytes, whereas the addition of 17-AAG, a pharmacologic inhibitor of Hsp90, attenuates Araloside C-induced cardioprotective effect.Araloside C (0.5-2.5 μM) concentration-dependently improves the functional recovery of the I/R hearts, including increase in the recovery of LVDP, dP/dtmax and heart rate throughout the reperfusion period, although the baseline mechanical parameters with Araloside C were not significantly different compared with those of the control condition.Araloside C could improve post-ischaemic cell shortening and Ca2+ transients from 2 to 8 μM.
Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury.
体外研究：
Araloside C also up-regulates the expression levels of Hsp90 and improved cell viability in hypoxia/reoxygenation-treated H9c2 cardiomyocytes, whereas the addition of 17-AAG, a pharmacologic inhibitor of Hsp90, attenuates Araloside C-induced cardioprotective effect.Araloside C (0.5-2.5 μM) concentration-dependently improves the functional recovery of the I/R hearts, including increase in the recovery of LVDP, dP/dtmax and heart rate throughout the reperfusion period, although the baseline mechanical parameters with Araloside C were not significantly different compared with those of the control condition.Araloside C could improve post-ischaemic cell shortening and Ca2+ transients from 2 to 8 μM.
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