产品
编 号:F388184
分子式:C7H4Cl3NO3
分子量:256.47
产品类型
结构图
CAS No: 55335-06-3
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产品详情
生物活性:
Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity.
体内研究:
Pharmacokinetic AnalysisTriclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) .Animal Model:3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey
Dosage:0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey)
Administration:Oral gavage (beagle dog); intravenous (rhesus monkey)
Result:T1/2s of 25 and 6.3 h for dogs and a monkey, respectively.
体外研究:
Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells.