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编 号:F388051
分子式:C11H11Cl2N3O
分子量:272.13
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
Muzolimine (BAY-g 282) is a slow and long lasting diuresis agent. Muzolimine produces a diuresis in the loop of Henle and also shows anti-hypertensive effects. Muzolimine can be used for the research of cardiovascular disease.

体内研究:
Muzolimine (0-18 mg/kg; p.o. 7-times per week for 3 months) shows a marked diuresis effect in dogs.Animal Model:3 male and 3 female dogs
Dosage:0, 2, 6, 8 and 18 mg/kg
Administration:Oral gavage; 7 times per week for 3 months
Result:Showed significant diuretic results, and increased the water intake of dogs.

体外研究:
Muzolimine (10 μM-1 mM) dose-dependently inhibits ion transport in Ehrlich cells.
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