产品
编 号:F387859
分子式:C23H22N4O
分子量:370.45
产品类型
结构图
CAS No: 552332-71-5
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产品详情
生物活性:
DB07107 is a potent agent resistant T315I mutant Bcr-Abl tyrosine kinase inhibitor. DB07107 is also a potent Akt1 inhibitor with an IC50 value of 360 nM.
体外研究:
DB07107 is more effective in blocking drug-resistant T315I mutant than the wild-type Bcr-Abl. DB07107 (C23H22N4O) from DrugBank showed the highest binding energy with XP score of -14.045 kcal/mol.