产品
编 号：F386855
分子式：C16H12O6
分子量：300.26
分子式：C16H12O6
分子量：300.26
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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50mg
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结构图
CAS No: 548-77-6
产品详情
生物活性：
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
体外研究：
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsoniiBenth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECsin a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively.
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
体外研究：
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsoniiBenth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECsin a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively.
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