产品
编 号:F043267
分子式:C37H53NO8
分子量:639.82
产品类型
结构图
CAS No: 113507-06-5
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产品详情
生物活性:
Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk.
体内研究:
Moxidectin (0.2 mg/kg; 口服或静脉注射; 单剂量) 在 mdr1ac 小鼠中血浆和脑中的浓度均高于野生小鼠。