产品
编 号:F384179
分子式:C22H28O2
分子量:324.46
产品类型
结构图
CAS No: 54048-10-1
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产品详情
生物活性:
Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).
体外研究:
Etonogestrel inhibits fertility by inhibiting the release of luteinizing hormone (LH), one of the reproductive hormones important in ovulation.Etonogestrel also increases the viscosity of cervical mucus, which hinders the passage of spermatozoa and alters the lining of the uterus to prevent implantation of a fertilized egg into the endometrium.Etonogestrel, a progestin, is a substrate of the CYP 3A4 oxidase system.Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).