产品
编 号：F043019
分子式：C20H25N3O2
分子量：339.43
分子式：C20H25N3O2
分子量：339.43
产品类型
规格
价格
是否有货
结构图
CAS No: 113-42-8
产品详情
生物活性：
Methylergometrine (Methylergonovine) is an orally active 5-HT2B ligand agonist. The distribution half-life of Methylergometrine is only 1-2 min. Methylergometrine can be used as an oxytocin to treat uterine atony.
体内研究：
Methylergometrine (0.2 mg/kg；静脉注射；单剂量) 出现在家兔子宫、肝脏和肾脏中，平均浓度分别为 34 ng/g、80 ng/g 和 203 ng/g (给药 30 min 后)。Methylergometrine 在家兔中的药代动力学 (PK) 参数CO ng/mLK12/minK21/minKe1/min
mean755.30.5770.1800.140
S.D.215.80.0980.0360.069
T1/2α/minT1/2β/minVdc L/kgVdss L/kgVdβ L/kgAUCtot (ng/mL)?minCLtot mL/min
mean0.9126.340.291.131.446060.8883.74
S.D.0.359.480.090.300.552005.3017.86
Methylergometrine (Methylergonovine) is an orally active 5-HT2B ligand agonist. The distribution half-life of Methylergometrine is only 1-2 min. Methylergometrine can be used as an oxytocin to treat uterine atony.
体内研究：
Methylergometrine (0.2 mg/kg；静脉注射；单剂量) 出现在家兔子宫、肝脏和肾脏中，平均浓度分别为 34 ng/g、80 ng/g 和 203 ng/g (给药 30 min 后)。Methylergometrine 在家兔中的药代动力学 (PK) 参数CO ng/mLK12/minK21/minKe1/min
mean755.30.5770.1800.140
S.D.215.80.0980.0360.069
T1/2α/minT1/2β/minVdc L/kgVdss L/kgVdβ L/kgAUCtot (ng/mL)?minCLtot mL/min
mean0.9126.340.291.131.446060.8883.74
S.D.0.359.480.090.300.552005.3017.86
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备