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编 号：F382545
分子式：C21H20ClNO6
分子量：417.84
分子式：C21H20ClNO6
分子量：417.84
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CAS No: 53552-05-9
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生物活性：
(-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.
体内研究：
(-)-Bicuculline methochloride (0.6 nmol/rat) attenuates the antiallodynic effect of Neurotropin.Animal Model:Rat L5-SNL model
Dosage:0.6 nmol/rat
Administration:Intrathecal injection, 5 minutes before administration of Neurotropin (100 NU/kg, i.v.)
Result:Attenuated the antiallodynic effect of Neurotropin.
(-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.
体内研究：
(-)-Bicuculline methochloride (0.6 nmol/rat) attenuates the antiallodynic effect of Neurotropin.Animal Model:Rat L5-SNL model
Dosage:0.6 nmol/rat
Administration:Intrathecal injection, 5 minutes before administration of Neurotropin (100 NU/kg, i.v.)
Result:Attenuated the antiallodynic effect of Neurotropin.
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