产品
编 号:F381304
分子式:C10H8O3
分子量:176.17
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价格
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10mM*1mL in DMSO
询价
询价
100mg
194
In-stock
500mg
400
In-stock
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产品详情
生物活性:
Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.

体外研究:
Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
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