产品
编 号:F380124
分子式:C10H8NNaO7S2
分子量:341.29
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5mg
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10mg
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50mg
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100mg
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生物活性:
CaMKP inhibitor sodium (compound 5) is an inhibitor of Ca2+/neutral protein-dependent protein concentration (CaMKP) and its nuclear type (CaMKP-N) (IC50: 6.4 μM, CaMKP; 6.6 μM, CaMKP-N). CaMKP is one type of Ser/Thr protein, which can be passed through to remove the oxidized oxidized protein (CaMK). CaMKP inhibitor sodium inhibits CaMKP mediated phospho-CaMKI hydrolysis, unaffectes protein phosphoric acid 2C (PP2C) and calcineurin (CaN).

体外研究:
CaMKP inhibitor sodium(10 μM;6 小时)抑制 Neuro2a 细胞中表达的 CaMKP-N。CaMKP inhibitor sodium(2.5 μM、5 μM)抑制 Neuro2a 细胞中 CaMKP 活性而不是 PP2C 活性。
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