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编 号:F379485
分子式:C22H26O6
分子量:386.44
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生物活性:
Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities.

体外研究:
Treatment of mesenchymal stem cells (MSCs) with Eudesmin (20, 40, and 80μM) disturbs adipogenesis via suppression of S6K1 signaling pathway. Eudesmin treatment inhibits activation and nuclear translocation of S6K1. S6K1-mediated phosphorylation of H2B at serine 36 (H2BS36p) is reduced upon Eudesmin treatment.
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