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编 号:F379042
分子式:C21H19FN2O2
分子量:350.39
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生物活性:
PDE4-IN-11 is an inhibitor of phosphodiesterase isoenzyme 4 (PDE4). PDE4-IN-11 displays highly effective bronchodilatory and anti-inflammatory properties, can be used for obstructive or inflammatory airway diseases research.

体外研究:
PDE4-IN-11 (example 12) exerts function in the monocrotaline reversal model of pulmonary hypertension.PDE4-IN-11 (compound A1) displays anti-inflammatory, anti-airways hyperreactivity and bronch odilator properties. PDE4-IN-11 also possesses immunosuppressive and TNFα secretion inhibitory activities.
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