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编 号：F378950
分子式：C9H13NO3.xH2O4S
分子式：C9H13NO3.xH2O4S
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CAS No: 52455-32-0
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生物活性：
L-Epinephrine ((-)-Epinephrine, L-Adrenaline) sulfate is a orally active hormone secreted by the medulla of the adrenal glands. L-Epinephrine sulfate is an α-adrenergic and β-adrenergic receptor agonist. L-Epinephrine sulfate can be used in the research of anaphylaxis. L-Epinephrine sulfate has the potential for the research of cardiac arrest.
体内研究：
L-Epinephrine sulfate (0.75, 1.5, 3 mg/kg; i.p.) exerts oxidative and nitrative stress in rats, increased damage to lipids and proteins, and damage of cardiomyocytes and cytogenetic damage in rats.L-Epinephrine sulfate (0.02, 0.03 mg/kg) increases ABP’s and to some extent also CePP, but significantly decreases organ and brain perfusion in adult pigs.L-Epinephrine sulfate (0.1 mg/kg; s.c.) enhances memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory.Animal Model:220-280 g, 18 weeks Wistar rats
Dosage:0.75, 1.5, 3 mg/kg
Administration:IP
Result:Induced a significant rise in CAT activity, MDA level, PCC, NO2?, and 3-NT and a significant decrease in SOD activity, and exerted an increase in total activity of LDH, LDH1, and LDH2 isoenzymes.
Animal Model:24-25 month male Fischer-344 rats
Dosage:0.1 mg/kg
Administration:S.c.
Result:Enhanced memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory.
L-Epinephrine ((-)-Epinephrine, L-Adrenaline) sulfate is a orally active hormone secreted by the medulla of the adrenal glands. L-Epinephrine sulfate is an α-adrenergic and β-adrenergic receptor agonist. L-Epinephrine sulfate can be used in the research of anaphylaxis. L-Epinephrine sulfate has the potential for the research of cardiac arrest.
体内研究：
L-Epinephrine sulfate (0.75, 1.5, 3 mg/kg; i.p.) exerts oxidative and nitrative stress in rats, increased damage to lipids and proteins, and damage of cardiomyocytes and cytogenetic damage in rats.L-Epinephrine sulfate (0.02, 0.03 mg/kg) increases ABP’s and to some extent also CePP, but significantly decreases organ and brain perfusion in adult pigs.L-Epinephrine sulfate (0.1 mg/kg; s.c.) enhances memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory.Animal Model:220-280 g, 18 weeks Wistar rats
Dosage:0.75, 1.5, 3 mg/kg
Administration:IP
Result:Induced a significant rise in CAT activity, MDA level, PCC, NO2?, and 3-NT and a significant decrease in SOD activity, and exerted an increase in total activity of LDH, LDH1, and LDH2 isoenzymes.
Animal Model:24-25 month male Fischer-344 rats
Dosage:0.1 mg/kg
Administration:S.c.
Result:Enhanced memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory.
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