产品
编 号：F378906
分子式：C6H11NO2S
分子量：161.22
分子式：C6H11NO2S
分子量：161.22
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 52438-09-2
产品详情
生物活性：
S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model. S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway. S-1-Propenyl-L-cysteine is orally active.
体内研究：
S-1-Propenyl-L-cysteine (6.5 mg/kg，口服) 降低自发性高血压大鼠的收缩压 (SBP)，改变组氨酸代谢并通过中枢组胺受体 (H3R) 发挥抗高血压作用。Animal Model:spontaneously hypertensive rats (SHR)
Dosage:6.5? mg/kg
Administration:p.o., single dosage
Result:Reduced blood pressure and produced a change in metabolites.Increased histidine levels after 1.5-3 h after administration.
体外研究：
S-1-Propenyl-L-cysteine NO 依赖性地上调 HMOX1 水平，BACH1 下调，导致 BACH1 在细胞核中降解。 S-1-Propenyl-L-cysteine 通过变性和激活自噬 (autophagy) 诱导 MyD88 降解，从而抑制脂多糖 (LPS) 诱导的 TLR4 信号通路。
S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model. S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway. S-1-Propenyl-L-cysteine is orally active.
体内研究：
S-1-Propenyl-L-cysteine (6.5 mg/kg，口服) 降低自发性高血压大鼠的收缩压 (SBP)，改变组氨酸代谢并通过中枢组胺受体 (H3R) 发挥抗高血压作用。Animal Model:spontaneously hypertensive rats (SHR)
Dosage:6.5? mg/kg
Administration:p.o., single dosage
Result:Reduced blood pressure and produced a change in metabolites.Increased histidine levels after 1.5-3 h after administration.
体外研究：
S-1-Propenyl-L-cysteine NO 依赖性地上调 HMOX1 水平，BACH1 下调，导致 BACH1 在细胞核中降解。 S-1-Propenyl-L-cysteine 通过变性和激活自噬 (autophagy) 诱导 MyD88 降解，从而抑制脂多糖 (LPS) 诱导的 TLR4 信号通路。
产品资料
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