产品
编 号:F378434
分子式:C15H20O8
分子量:328.31
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1mg
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5mg
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10mg
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生物活性:
Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10?μM.

体内研究:
In mice, the LD50 reported for anisatin ranges from 0.76 to 1?mg/kg (po and ip).

体外研究:
Anisatin inhibits [3H]diazepam binding enhanced by either GABA or pentobarbital, without affecting the basal specific binding to rat brain membranes.
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