产品
编 号：F377476
分子式：C15H10O7
分子量：302.24
分子式：C15H10O7
分子量：302.24
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 520-31-0
产品详情
生物活性：
Tricetin is a potent competitive inhibitor of the Keap1-Nrf2 Protein Protein Interaction (PPI). Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway.
体外研究：
Tricetin is mainly found in natural plants such as?Ginkgo biloba?L.,?Carica papaya?L. and?Murraya exotica?L.?Tricetin activates the Nrf2/HO-1 pathway to protect cells from oxidative stress. Tricetin possessed the protective effect on dopamine neurons of?C. elegans. Tricetin has?cytostatic?properties and anti-metastatic activity of various?solid tumors.Pretreatment?with Tricetin (20, 40, and 80 μM; for 4 hours) significantly improves 6-OHDA (200?μM)-induced SH-SY5Y cells viability and suppresses mitochondria-mediated apoptosis.Tricetin (80?μM; for 1, 2 and 4?h) markedly decreased the expressions of p-JNK and p-p38.
Tricetin is a potent competitive inhibitor of the Keap1-Nrf2 Protein Protein Interaction (PPI). Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway.
体外研究：
Tricetin is mainly found in natural plants such as?Ginkgo biloba?L.,?Carica papaya?L. and?Murraya exotica?L.?Tricetin activates the Nrf2/HO-1 pathway to protect cells from oxidative stress. Tricetin possessed the protective effect on dopamine neurons of?C. elegans. Tricetin has?cytostatic?properties and anti-metastatic activity of various?solid tumors.Pretreatment?with Tricetin (20, 40, and 80 μM; for 4 hours) significantly improves 6-OHDA (200?μM)-induced SH-SY5Y cells viability and suppresses mitochondria-mediated apoptosis.Tricetin (80?μM; for 1, 2 and 4?h) markedly decreased the expressions of p-JNK and p-p38.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备