产品
编 号：F376699
分子式：C5H7NaO3S
分子量：170.16
分子式：C5H7NaO3S
分子量：170.16
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 51828-97-8
产品详情
生物活性：
MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor. MTOB sodium attenuates repetitive head injury-elicited neurologic dysfunction and neuroinflammation via inhibition of the transactivation activity of CtBP1 and CtBP2. MTOB sodium antagonizes the transcriptional regulatory activity of CtBP1 and CtBP2 by eviction from their target promoters in breast cancer cell lines.
体内研究：
MTOB sodium (860 mg/kg; IP, at 1 h and 18 h after the first injury) effectively suppresses the increases duration of righting reflex, and significantly decreased neurological severity score (NSS) scores.Animal Model:C57BL/6 mice (traumatic brain injury)
Dosage:860 mg/kg
Administration:IP, at 1 h and 18 h after the first injury
Result:Effectively suppressed the increased duration of righting reflex, and significantly decreased NSS scores.
体外研究：
MTOB sodium (10 mM) causes significant derepression (PMTOB sodium 相关抗体:
MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor. MTOB sodium attenuates repetitive head injury-elicited neurologic dysfunction and neuroinflammation via inhibition of the transactivation activity of CtBP1 and CtBP2. MTOB sodium antagonizes the transcriptional regulatory activity of CtBP1 and CtBP2 by eviction from their target promoters in breast cancer cell lines.
体内研究：
MTOB sodium (860 mg/kg; IP, at 1 h and 18 h after the first injury) effectively suppresses the increases duration of righting reflex, and significantly decreased neurological severity score (NSS) scores.Animal Model:C57BL/6 mice (traumatic brain injury)
Dosage:860 mg/kg
Administration:IP, at 1 h and 18 h after the first injury
Result:Effectively suppressed the increased duration of righting reflex, and significantly decreased NSS scores.
体外研究：
MTOB sodium (10 mM) causes significant derepression (PMTOB sodium 相关抗体:
产品资料
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