产品
编 号:F376591
分子式:C16H13FN2O2
分子量:284.29
产品类型
结构图
CAS No: 518058-84-9
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产品详情
生物活性:
KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL).
体内研究:
KX1-004 (30 μM) provides significant protection against noise-induced temporary threshold shift (TTS), permanent threshold shift (PTS) and outer hair cells (OHC) loss.KX1-004 (50 mg/kg) is effective against noise exposure.