产品
编 号:F376405
分子式:C33H53N11O9
分子量:747.84
产品类型
结构图
CAS No: 51776-33-1
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产品详情
生物活性:
LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes.
体外研究:
The formation of LHRH 4-10, LHRH 7-10, and LHRH 6-10Co-incubation are inhibited by known enzyme inhibitors including Captopril (HY-B0368) (an ACE inhibitor), Thiorphan (HY-W013375) (an EP24.11 inhibitor), and Ethylenediaminetetraacetic acid (HY-Y0682) (an EP24.15 inhibitor).LH-RH (4-10) inhibits the binding of 125I-labeled GnRH to monoclonal antibody P81662 with an IC50 value of 23 pM.