产品
编 号:F375796
分子式:C30H37Cl2N7O6
分子量:662.56
产品类型
结构图
CAS No: 515846-21-6
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产品详情
生物活性:
SP4206 is an IL-2/IL-2Rα interaction inhibitor. SP4206 binds with high affinity (Kd=70 nM) to IL-2 and blocks binding to its natural receptor IL-2Rα (Kd=10 nM).
体外研究:
SP4206 binds the WT IL-2, IL-2 variant K35L/M39V, IL-2 variant P65A, and IL-2 variant V69A with EC50s of 68.8, 80.1, 117.0, and 10.4 nM, respectively.