产品
编 号：F375681
分子式：C12H22O10S
分子量：358.36
分子式：C12H22O10S
分子量：358.36
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 51555-87-4
产品详情
生物活性：
Thiodigalactoside (TDG) is an orally active and potent galectin (GAL) inhibitor with Kd values of 24 μM, 49 μM for GAL1 and GAL3, respectively. Thiodigalactoside, a non-metabolizable disaccharide, has anti-inflammatory and anti-cancer activity. Thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats.
体内研究：
Thiodigalactoside (TDG; 5?mg/kg; IP; once per week for 5 weeks) results in dramatic inhibition of HFD-induced body weight gain. Thiodigalactoside (5?mg/kg; oral; daily or weekly for 5 weeks) gave less reduction in body weight gain compare with i.p.. Animal Model:Five-week-old Sprague-Dawley (SD) male rats
Dosage:5?mg/kg
Administration:IP; once per week for 5 weeks
Result:Resulted in dramatic inhibition of HFD-induced body weight gain by inhibiting adipogenesis and lipogensis as well as by increasing expression of the proteins associated with thermogenesis and energy expenditure.
体外研究：
Thiodigalactoside (TDG; 250 and 500?μM) exhibits dose-dependent reduction of fat accumulation based on triglyceride (TG) content and Oil Red O (ORO) staining.
Thiodigalactoside (TDG) is an orally active and potent galectin (GAL) inhibitor with Kd values of 24 μM, 49 μM for GAL1 and GAL3, respectively. Thiodigalactoside, a non-metabolizable disaccharide, has anti-inflammatory and anti-cancer activity. Thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats.
体内研究：
Thiodigalactoside (TDG; 5?mg/kg; IP; once per week for 5 weeks) results in dramatic inhibition of HFD-induced body weight gain. Thiodigalactoside (5?mg/kg; oral; daily or weekly for 5 weeks) gave less reduction in body weight gain compare with i.p.. Animal Model:Five-week-old Sprague-Dawley (SD) male rats
Dosage:5?mg/kg
Administration:IP; once per week for 5 weeks
Result:Resulted in dramatic inhibition of HFD-induced body weight gain by inhibiting adipogenesis and lipogensis as well as by increasing expression of the proteins associated with thermogenesis and energy expenditure.
体外研究：
Thiodigalactoside (TDG; 250 and 500?μM) exhibits dose-dependent reduction of fat accumulation based on triglyceride (TG) content and Oil Red O (ORO) staining.
产品资料
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