产品
编 号：F375553
分子式：C7H10N2OS
分子量：170.23
分子式：C7H10N2OS
分子量：170.23
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
480
In-stock
500mg
720
In-stock
结构图
CAS No: 51-52-5
产品详情
生物活性：
Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research.
体内研究：
通过给予补充有 0.15%Propylthiouracil 的缺碘饮食，Propylthiouracil 可诱导成年 C57BL/6J 和野生 WSB/EiJ 雄性小鼠的甲状腺功能减退症。Animal Model:Adult C57BL/6J and wild-derived WSB/EiJ male mice (8-weeks old)
Dosage:1.5 g/kg diet
Administration:Iodine-deficient diet; for 7 weeks
Result:Induced hypothyroidism in adult C57BL/6J and wild-derived WSB/EiJ male mice.
体外研究：
Propylthiouracil (5.5-330 μg/mL；24 h) 在 U-937 细胞中以剂量依赖性方式诱导生长迟缓和细胞毒性。
Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research.
体内研究：
通过给予补充有 0.15%Propylthiouracil 的缺碘饮食，Propylthiouracil 可诱导成年 C57BL/6J 和野生 WSB/EiJ 雄性小鼠的甲状腺功能减退症。Animal Model:Adult C57BL/6J and wild-derived WSB/EiJ male mice (8-weeks old)
Dosage:1.5 g/kg diet
Administration:Iodine-deficient diet; for 7 weeks
Result:Induced hypothyroidism in adult C57BL/6J and wild-derived WSB/EiJ male mice.
体外研究：
Propylthiouracil (5.5-330 μg/mL；24 h) 在 U-937 细胞中以剂量依赖性方式诱导生长迟缓和细胞毒性。
产品资料
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