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编 号:F375087
分子式:C30H48O
分子量:424.7
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1mg
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5mg
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生物活性:
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively.

体内研究:
Taraxerone significantly lowers theplasma alcohol and acetaldehyde concentrationsin mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration.
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