产品
编 号：F374598
分子式：C5H12NO4P
分子量：181.13
分子式：C5H12NO4P
分子量：181.13
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CAS No: 51276-47-2
产品详情
生物活性：
Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity.
体内研究：
Glufosinate (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats.The Elimination of Glufosinate (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats.
体外研究：
Glufosinate (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs).Glufosinate (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM.Glufosinate impairs ependymal cell capability to synthetize cilia.
Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity.
体内研究：
Glufosinate (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats.The Elimination of Glufosinate (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats.
体外研究：
Glufosinate (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs).Glufosinate (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM.Glufosinate impairs ependymal cell capability to synthetize cilia.
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