产品
编 号:F373339
分子式:C17H21N3O3S
分子量:347.43
产品类型
结构图
CAS No: 509102-00-5
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产品详情
生物活性:
MIM-1 is an inhibitor of myeloid cell factor 1 (Mcl-1).
体外研究:
MIM-1 selectively targets the BH3 binding groove of Mcl-1, with Bak-dependent apoptotic activity. To estimate the sensitivity of HA and T98G cells to the apoptosis inhibitor MIM-1, the colorimetric MTT assay is used to detect cell viability and to determine the IC50 value. The IC50 value of the HA cell line is almost 5-fold lower (16.10 μM) compared with the IC50 of the T98G cell line (80.20 μM) after MIM-1 inhibitor treatment.