产品
编 号：F372524
分子式：C10H12N2O
分子量：176.22
分子式：C10H12N2O
分子量：176.22
产品类型
规格
价格
是否有货
1mg
480
In-stock
5mg
960
In-stock
10mg
1440
In-stock
25mg
2560
In-stock
50mg
3840
In-stock
结构图
CAS No: 50-67-9
产品详情
生物活性：
Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
体内研究：
Serotonin produces robust hypersensitivity compare to saline-treated controls (p<0.001). A significant increase in colonic 5-HT content is observed in IL-13-/- mice receiving Serotonin compare to IL-13-/- receiving vehicle following induction of DSS colitis.
体外研究：
Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin also inhibits catechol O-methyltransferase (COMT), an enzyme that contributes to modultion the perception of pain, via non-competitive binding to the site bound by catechol substrates with a binding affinity comparable to the binding affinity of catechol itself (Ki=?44 μM). Results show that addition of 100 μM of Serotonin decreases the reaction velocity of COMT.
Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
体内研究：
Serotonin produces robust hypersensitivity compare to saline-treated controls (p<0.001). A significant increase in colonic 5-HT content is observed in IL-13-/- mice receiving Serotonin compare to IL-13-/- receiving vehicle following induction of DSS colitis.
体外研究：
Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin also inhibits catechol O-methyltransferase (COMT), an enzyme that contributes to modultion the perception of pain, via non-competitive binding to the site bound by catechol substrates with a binding affinity comparable to the binding affinity of catechol itself (Ki=?44 μM). Results show that addition of 100 μM of Serotonin decreases the reaction velocity of COMT.
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