产品
编 号:F372210
分子式:C17H19N3O
分子量:281.35
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5mg
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生物活性:
Phentolamine is a potent, selective and orally active α1 adrenergic and α2 adrenergic receptor antagonist. Phentolamine can be used for the research of erectile dysfunction.

体内研究:
Phentolamine (5-20 mg/kg; i.p.) effectively inhibits the seizures elicited by strychnine (2 mg/kg, i.p.) and attenuates the seizure-potentiating effect of DOPS (4 mg/kg, i.p.) in mouse.Phentolamine (1 mg/kg; i.p.) increases insulin secretion by inhibition of b-cell a2A-adrenoceptors in mouse.Animal Model:WT mice
Dosage:1 mg/kg
Administration:IP
Result:Reduced blood glucose and increased insulin levels.
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