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编 号:F371284
分子式:C11H18ClN5S
分子量:287.81
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生物活性:
Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically stimulated overflow of 3H-noradrenaline from rat cortical slices, without affecting the basal overflow. Mezilamine acts as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist.

体外研究:
Mezilamine (1, 5, 10 μM) 导致 3H 刺激的溢出浓度依赖性增加,而不影响皮质切片的自发流出。
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