产品
编 号:F370799
分子式:C9H10O3
分子量:166.18
产品类型
结构图
CAS No: 501-97-3
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生物活性:
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
体内研究:
Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice.