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编 号:F370707
分子式:C27H19F4N5O3
分子量:537.47
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity。

体外研究:
GW768505A free base has inhibition for cancer cells growth in NCI-60 panel screening.GW768505A free base is an inhibitor of KDR and TIE2, shows potent inhibition (71–88% inhibition at 100 nM) of the tropomysin-related kinases TRKA, TRKB and TRKC.
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