产品
编 号:F370611
分子式:C23H25N3O4S
分子量:439.53
产品类型
结构图
CAS No: 501364-82-5
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产品详情
生物活性:
INO-1001 is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor. INO-1001 is a potent enhancer of radiation sensitivity and enhances radiation-induced cell killing by interfering with DNA repair mechanisms, resulting in necrotic cell death. INO-1001 has anti-tumor effects.
体外研究:
INO-1001 在中国仓鼠卵巢 AA8 (CHO) 细胞中的 IC50 为 0.05 μM。