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编 号:F370574
分子式:C33H35FN2O5
分子量:558.64
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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生物活性:
(3S,5S)-Atorvastatin is a inactive enantiomer of Atorvastatin. (3S,5S)-Atorvastatin can activate pregnane X receptor (PXR). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

体外研究:
Atorvastatin and its inactive enantiomer (3S,5S)-Atorvastatin increases CYP2B and CYP3A mRNA content with equal ability.(3S,5S)-Atorvastatin in 100 μM concentrations induces luciferase activity with an EC50 of 12.4 μM.Addition of (3S,5S)-Atorvastatin to the 2-formylphenylboronicacid (FPBA)/l-tryptophanol mixture induces an intensity enhancement of l-tryptophanol florescence.
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