产品
编 号:F370323
分子式:C11H16O2
分子量:180.24
产品类型
结构图
CAS No: 500-66-3
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产品详情
生物活性:
Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively.
体外研究:
Olivetol 抑制 CYP2C19 活性的 (S)-mephenytoin 4'-hydroxylase 活性,IC50 为 15.3 μM,Ki 为 2.71 μM。Olivetol 还抑制重组 CYP2D6 的 AMMC O-去甲基化酶活性,IC50 为 7.21 μM,Ki 为 2.87 μM。 Olivetol 是大麻素受体 CB1 和 CB2 的竞争性抑制剂。