产品
编 号:F369849
分子式:C6H11NO2
分子量:129.16
产品类型
结构图
CAS No: 498-95-3
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产品详情
生物活性:
Nipecotic acid ((±)-β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro. Nipecotic acid can also directly activate GABAA-like chloride channels, with an EC50 of approximately 300?μM.
体内研究:
Nipecotic acid does not readily cross the blood-brain barrier (BBB).
体外研究:
Nipecotic acid (1?mM) activated inward unitary currents when applied to outside-out patches of paraventricular neurones.