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编 号:F041632
分子式:C25H36N4O
分子量:408.58
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
Dynole 34-2 is a dynamin GTPase inhibitor (IC50s=6.9 and 14.2 μM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME).
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