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编 号:F368464
分子式:C20H30ClN5O4
分子量:439.94
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MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 μM. MRS2395 enhances platelet dense granule release in response to TRAP-6.
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