产品
编 号:F368383
分子式:C10H6N4O2
分子量:214.18
产品类型
结构图
CAS No: 490-59-5
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产品详情
生物活性:
Alloxazine is a selective A2b antagonist. Alloxazine completely block 5’N-Ethylcarboxamido adenosine (NECA)-mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer.
体内研究:
Alloxazine (1 μmol/L; cortical surface suffusion for 0-20 min) suppresses NECA-induced vasodilation.Animal Model:Male Sprague-Dawley rats
Dosage:1 μmol/L
Administration:Cortical surface suffusion; 1 μmol/L once
Result:Significantly suppressed vasodilation with increased EC25 value of 0.60 μmol/L.
体外研究:
Alloxazine (0-30 μM, 20 min) inhibits cyclic AMP production in PGT-β cells.