产品
编 号：F368250
分子式：C31H33N3O5
分子量：527.61
分子式：C31H33N3O5
分子量：527.61
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 489415-96-5
产品详情
生物活性：
SBC-115076 is a potent proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PCSK9 is a proprotein convertase, which plays a crucial role in LDL receptor metabolism.
体内研究：
SBC-115076 (4 mg/kg；皮下注射；每日一次，持续 3 周) 减少高脂肪喂养大鼠的肥胖和血脂异常，并改善胰岛素敏感性。Animal Model:Female Wistar rats (high-fat diet (HFD)- fed)
Dosage:4 mg/kg
Administration:S.c.; daily for 3 weeks
Result:Superior to atorvastatin in instigating weight loss, cholesterol reduction, and attenuation of mitochondrial oxidative stress in oxidative muscle fibers of obese female rats.
SBC-115076 is a potent proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PCSK9 is a proprotein convertase, which plays a crucial role in LDL receptor metabolism.
体内研究：
SBC-115076 (4 mg/kg；皮下注射；每日一次，持续 3 周) 减少高脂肪喂养大鼠的肥胖和血脂异常，并改善胰岛素敏感性。Animal Model:Female Wistar rats (high-fat diet (HFD)- fed)
Dosage:4 mg/kg
Administration:S.c.; daily for 3 weeks
Result:Superior to atorvastatin in instigating weight loss, cholesterol reduction, and attenuation of mitochondrial oxidative stress in oxidative muscle fibers of obese female rats.
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