产品
编 号：F368118
分子式：C6H12Br2O4
分子量：307.97
分子式：C6H12Br2O4
分子量：307.97
产品类型
规格
价格
是否有货
结构图
CAS No: 488-41-5
产品详情
生物活性：
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. Mitobronitol has potential for myelosuppression associated with significantly decreased risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia.
体内研究：
Mitobronitol (850 mg/kg; i.p.; single dose) improves spleen cells to mitogens and enhances thymus regeneration in mice model.Animal Model:Female BALB/c mice (8-10 weeks old)
Dosage:850 mg/kg; 1500 mg/kg (suspended in 5% Tween 80 in saline, 0.5 mL)
Administration:Intraperitoneal injection; single dose
Result:Showed effect on the in vitro proliferative response of spleen cells to mitogens at 850 mg/kg.Enhanced thymus regeneration and was earlier than control, with the starting resititution time-course of 2 weeks and subtotal resititution time course of 3 weeks under 1500 mg/kg dose.
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. Mitobronitol has potential for myelosuppression associated with significantly decreased risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia.
体内研究：
Mitobronitol (850 mg/kg; i.p.; single dose) improves spleen cells to mitogens and enhances thymus regeneration in mice model.Animal Model:Female BALB/c mice (8-10 weeks old)
Dosage:850 mg/kg; 1500 mg/kg (suspended in 5% Tween 80 in saline, 0.5 mL)
Administration:Intraperitoneal injection; single dose
Result:Showed effect on the in vitro proliferative response of spleen cells to mitogens at 850 mg/kg.Enhanced thymus regeneration and was earlier than control, with the starting resititution time-course of 2 weeks and subtotal resititution time course of 3 weeks under 1500 mg/kg dose.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备