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编 号：F367854
分子式：C19H22N2
分子量：278.39
分子式：C19H22N2
分子量：278.39
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CAS No: 486-12-4
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生物活性：
Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis.
体内研究：
Triprolidine (292.81-1467.20 μg/kg; i.p.; Male Sprague-Dawley rat) produces a dose-dependent effect of spinal motor and sensory block in rats.Animal Model:Male Sprague-Dawley rat (300-350 g)
Dosage:292.81, 488.02, 733.60, 1098.83 and 1467.20 μg/kg
Administration:Intrathecal injection
Result:Elicited spinal block in a dose-dependent.
体外研究：
Triprolidine (maturing human dendritic cells) can antagonist histamine H1 and decreases the expression of CD45.
Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis.
体内研究：
Triprolidine (292.81-1467.20 μg/kg; i.p.; Male Sprague-Dawley rat) produces a dose-dependent effect of spinal motor and sensory block in rats.Animal Model:Male Sprague-Dawley rat (300-350 g)
Dosage:292.81, 488.02, 733.60, 1098.83 and 1467.20 μg/kg
Administration:Intrathecal injection
Result:Elicited spinal block in a dose-dependent.
体外研究：
Triprolidine (maturing human dendritic cells) can antagonist histamine H1 and decreases the expression of CD45.
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