产品
编 号:F367442
分子式:C21H20O12
分子量:464.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
200
In-stock
5mg
400
In-stock
10mg
560
In-stock
25mg
960
In-stock
50mg
1440
In-stock
100mg
2160
In-stock
结构图
联系客服
产品详情
生物活性:
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies.

体外研究:
Isoquercetin (Quercetin 3-glucoside;5 -20 μM;24 h) 显著降低乙醇诱导的细胞毒性,保护肝细胞免受乙醇刺激的肝损伤。Isoquercetin (10 μM;预处理 1 h) 显著下调 HepG2 细胞中乙醇诱导的 iNOS 蛋白表达水平。
产品资料