产品
编 号：F365008
分子式：C7H11NO4
分子量：173.17
分子式：C7H11NO4
分子量：173.17
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规格
价格
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结构图
CAS No: 477331-06-9
产品详情
生物活性：
cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively.
体内研究：
cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats.
体外研究：
cis-ACPD is a selective group II mGluR agonist, with EC50s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively.cis-ACPD (1-1000 μM; 60 min) stimulates hydrolysis of 3H-phosphoinositide.
cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively.
体内研究：
cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats.
体外研究：
cis-ACPD is a selective group II mGluR agonist, with EC50s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively.cis-ACPD (1-1000 μM; 60 min) stimulates hydrolysis of 3H-phosphoinositide.
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