产品
编 号：F364986
分子式：C21H25NO5
分子量：371.43
分子式：C21H25NO5
分子量：371.43
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 477-30-5
产品详情
生物活性：
Demecolcine is a potent mitotic inhibitor with an IC50 value of 2.4 μM for inhibition of tubulin polymerization. Colcemid (Demecolcine) can interact with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth. Colcemid (Demecolcine) can be used for inflammatory disorders and cancer research.
体内研究：
Demecolcine (0.3 mg/kg，腹腔注射) 在经 Demecolcine 腹腔注射处理后的小鼠中提高了分裂 II 期低倍性的发生率。Animal Model:Mice
Dosage:0.3 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Elevated 7.8-8-fold of the hypoploid and hyperploid frequencies in metaphase II cells relative to controls.
体外研究：
Demecolcine (0.1-0.25 μg/ml, 1小时) 降低小鼠、大鼠和青蛙精母细胞的分裂 II 期补体的低倍性频率。
Demecolcine is a potent mitotic inhibitor with an IC50 value of 2.4 μM for inhibition of tubulin polymerization. Colcemid (Demecolcine) can interact with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth. Colcemid (Demecolcine) can be used for inflammatory disorders and cancer research.
体内研究：
Demecolcine (0.3 mg/kg，腹腔注射) 在经 Demecolcine 腹腔注射处理后的小鼠中提高了分裂 II 期低倍性的发生率。Animal Model:Mice
Dosage:0.3 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Elevated 7.8-8-fold of the hypoploid and hyperploid frequencies in metaphase II cells relative to controls.
体外研究：
Demecolcine (0.1-0.25 μg/ml, 1小时) 降低小鼠、大鼠和青蛙精母细胞的分裂 II 期补体的低倍性频率。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备