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编 号:F364951
分子式:C17H17NO5
分子量:315.32
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生物活性:
Hippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect against topoisomerase I (Top I) with an IC50 at 7.25?μg/mL. Antiproliferative and anticancer activities.

体外研究:
Hippeastrine strongly inhibits the proliferation of HT-29 and Hep G2 cells in an intuitive dose-dependent manner with the IC50s at 3.98 μg/mL and 11.85 μg/mL, respectively, and also induces significant cellular morphological changes, which further validate our screening method and the potent antineoplastic effects.
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