产品
编 号:F364436
分子式:C27H46O2
分子量:402.65
产品类型
结构图
CAS No: 474-73-7
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产品详情
生物活性:
24(S)-Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S)-Hydroxycholesterol (24S-OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24(S)-Hydroxycholesterol (24S-OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism that does not overlapthat of other allosteric modulators.
体外研究:
24(S)-Hydroxycholesterol (1, 10, 30 μM) 可保护离体大鼠视网膜免受静水压力升高的损伤。