产品
编 号：F041131
分子式：C82H108ClN17O14
分子量：1591.29
分子式：C82H108ClN17O14
分子量：1591.29
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 112568-12-4
产品详情
生物活性：
Antide (D-21074) is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.
体内研究：
Antide (subcutaneously; 1, 3, 6, 10 and 15 mg/kg; once or on 5 consecutive days) can induce a long-term chemical castration in adult male rats and cynomolgus monkeys.Animal Model:Cynomolgus monkey and rat
Dosage:1, 3, 6, 10 and 15 mg/kg
Administration:Subcutaneous, once or on 5 consecutive days
Result:Had a dose-dependent inhibitory effect on serum concentration of LH (only rat) and testosterone and on the weights of the testes, prostates and seminal vesicles.Achieved long-lasting castration-like effects at concentrations between 6 (less than or equal to 8 weeks) and 15 mg/kg (greater than 8 weeks) in the rat. Induced a prolonged inhibitory effect only at 15 mg/kg and the duration was only 2-3 weeks in the cynomolgus monkey.
Antide (D-21074) is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.
体内研究：
Antide (subcutaneously; 1, 3, 6, 10 and 15 mg/kg; once or on 5 consecutive days) can induce a long-term chemical castration in adult male rats and cynomolgus monkeys.Animal Model:Cynomolgus monkey and rat
Dosage:1, 3, 6, 10 and 15 mg/kg
Administration:Subcutaneous, once or on 5 consecutive days
Result:Had a dose-dependent inhibitory effect on serum concentration of LH (only rat) and testosterone and on the weights of the testes, prostates and seminal vesicles.Achieved long-lasting castration-like effects at concentrations between 6 (less than or equal to 8 weeks) and 15 mg/kg (greater than 8 weeks) in the rat. Induced a prolonged inhibitory effect only at 15 mg/kg and the duration was only 2-3 weeks in the cynomolgus monkey.
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