产品
编 号：F363805
分子式：C30H48O3
分子量：456.7
分子式：C30H48O3
分子量：456.7
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 471-66-9
产品详情
生物活性：
alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research.
体内研究：
alpha-Boswellic acid (3 或 10 mg/kg, 腹腔注射) 可降低 2,4-二硝基氯苯诱导的 BALB/c 小鼠的表皮增厚、肥大细胞数量和真皮浸润。alpha-Boswellic acid (200 mg/kg, 灌胃) 对乙醇诱导的大鼠胃损伤具有保护作用。Animal Model:2,4-Dinitrochlorobenzene-Induced Atopic-like Dermatitis in BALB/c Mice
Dosage:3 or 10 mg/kg
Administration:i.p.
Result:Reduced the severity of the AD-like symptoms.Attenuated the increase in ear thickness and decreased cutaneous TEWL in DNCB-treated mice.
Animal Model:Ethanol-induced gastric injury in rats
Dosage:200 mg/kg
Administration:i.g.
Result:Reduced injuries associated with the administration of ethanol, gastric juice acidity and the formation of MDA and increased CAT activity and SOD activity and the level of NO and PGE-2 in a dose-depended manner.Increased the expression of both Nrf2 and HO-1.
体外研究：
alpha-Boswellic acid (1, 3, 10 μM, 20 min) 可以降低 HaCaT 细胞 TNF-α/IFN-γ 刺激后的细胞因子(IL-1β、IL-6和IL-8) 的表达水平。
alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research.
体内研究：
alpha-Boswellic acid (3 或 10 mg/kg, 腹腔注射) 可降低 2,4-二硝基氯苯诱导的 BALB/c 小鼠的表皮增厚、肥大细胞数量和真皮浸润。alpha-Boswellic acid (200 mg/kg, 灌胃) 对乙醇诱导的大鼠胃损伤具有保护作用。Animal Model:2,4-Dinitrochlorobenzene-Induced Atopic-like Dermatitis in BALB/c Mice
Dosage:3 or 10 mg/kg
Administration:i.p.
Result:Reduced the severity of the AD-like symptoms.Attenuated the increase in ear thickness and decreased cutaneous TEWL in DNCB-treated mice.
Animal Model:Ethanol-induced gastric injury in rats
Dosage:200 mg/kg
Administration:i.g.
Result:Reduced injuries associated with the administration of ethanol, gastric juice acidity and the formation of MDA and increased CAT activity and SOD activity and the level of NO and PGE-2 in a dose-depended manner.Increased the expression of both Nrf2 and HO-1.
体外研究：
alpha-Boswellic acid (1, 3, 10 μM, 20 min) 可以降低 HaCaT 细胞 TNF-α/IFN-γ 刺激后的细胞因子(IL-1β、IL-6和IL-8) 的表达水平。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备